Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

Peroxisome proliferator-activated receptor δ (PPARδ) is a ligand-activated transcription factor that has an important role in lipid metabolism. Activation of PPARδ stimulates fatty acid oxidation in adipose tissue and skeletal muscle and improves dyslipidemia in mice and humans. PPARδ is highly expr...

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Pubblicato in:Sci Rep
Autori principali: Doktorova, Marcela, Zwarts, Irene, Zutphen, Tim van, Dijk, Theo H. van, Bloks, Vincent W., Harkema, Liesbeth, Bruin, Alain de, Downes, Michael, Evans, Ronald M., Verkade, Henkjan J., Jonker, Johan W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429805/
https://ncbi.nlm.nih.gov/pubmed/28404991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00889-z
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