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Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration

Nitroaromatics are among the most important and commonly used chemicals but their production often suffers from multiple unsolved challenges. We have previously described the development of biocatalytic nitration processes driven by an engineered P450 TxtE fusion construct. Herein we report the crea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zuo, Ran, Zhang, Yi, Jiang, Chao, Hackett, John C., Loria, Rosemary, Bruner, Steven D., Ding, Yousong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429796/
https://ncbi.nlm.nih.gov/pubmed/28405004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00897-z
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