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Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

BACKGROUND: Epidemiological studies of DNA methylation profiles may uncover the molecular mechanisms through which genetic and environmental factors contribute to the risk of multifactorial diseases. There are two types of commonly used DNA bioresources, peripheral blood cells (PBCs) and EBV-transfo...

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Veröffentlicht in:Hum Genomics
Hauptverfasser: Taniguchi, Itsuki, Iwaya, Chihiro, Ohnaka, Keizo, Shibata, Hiroki, Yamamoto, Ken
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429538/
https://ncbi.nlm.nih.gov/pubmed/28499412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-017-0106-6
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