TRAIL mutant membrane penetrating peptide alike-MuR6-TR enhances the antitumor effects of TRAIL in pancreatic carcinoma both in vitro and in vivo

To remedy the drug resistance of natural tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and enhance its antitumor effects, we prepared a type of TRAIL mutant membrane penetrating peptide alike (TMPPA)-TRAIL mutant R6 (MuR6-TR) by mutating the N-terminal of the soluble TRAIL gene seq...

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Vydáno v:Int J Mol Med
Hlavní autoři: Sun, Lei, Chen, Chen, Zhu, Aijing, Huang, Ying, Zhu, Hong, Yi, Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428941/
https://ncbi.nlm.nih.gov/pubmed/28487979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2968
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