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Novel insights into the interaction of UBA5 with UFM1 via a UFM1-interacting sequence
The modification of proteins by ubiquitin-fold modifier 1 (UFM1) is implicated in many human diseases. Prior to conjugation, UFM1 undergoes activation by its cognate activating enzyme, UBA5. UBA5 is a non-canonical E1 activating enzyme that possesses an adenylation domain but lacks a distinct cystei...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428781/ https://ncbi.nlm.nih.gov/pubmed/28360427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00610-0 |
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