The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage

The deubiquitinating enzyme associated molecule with the SH3 domain of STAM (AMSH) is crucial for the removal of ubiquitin molecules during receptor-mediated endocytosis and lysosomal receptor sorting. AMSH interacts with signal transducing adapter molecule (STAM) 1 or 2, which enhances the activity...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Baiady, Nardeen, Padala, Prasanth, Mashahreh, Bayan, Cohen-Kfir, Einav, Todd, Emily A., Du Pont, Kelly E., Berndsen, Christopher E., Wiener, Reuven
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722476/
https://ncbi.nlm.nih.gov/pubmed/26601948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689869
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