Mobilization of allogeneic peripheral blood stem cell donors with intravenous plerixafor mobilizes a unique graft

A single subcutaneous (SC) injection of plerixafor results in rapid mobilization of hematopoietic progenitors, but fails to mobilize 33% of normal allogeneic sibling donors in 1 apheresis. We hypothesized that changing the route of administration of plerixafor from SC to IV may overcome the low stem...

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Foilsithe in:Blood
Main Authors: Schroeder, Mark A., Rettig, Michael P., Lopez, Sandra, Christ, Stephanie, Fiala, Mark, Eades, William, Mir, Fazia A., Shao, Jin, McFarland, Kyle, Trinkaus, Kathryn, Shannon, William, Deych, Elena, Yu, Jinsheng, Vij, Ravi, Stockerl-Goldstein, Keith, Cashen, Amanda F., Uy, Geoffrey L., Abboud, Camille N., Westervelt, Peter, DiPersio, John F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2017
Ábhair:
Transplantation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428459/
https://ncbi.nlm.nih.gov/pubmed/28292947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-739722
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