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The role of axonal Kv1 channels in CA3 pyramidal cell excitability

Axonal ion channels control spike initiation and propagation along the axon and determine action potential waveform. We show here that functional suppression of axonal Kv1 channels with local puff of dendrotoxin (DTx), laser or mechanical axotomy significantly increased excitability measured in the...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Rama, Sylvain, Zbili, Mickael, Fékété, Aurélie, Tapia, Mónica, Benitez, Maria José, Boumedine, Norah, Garrido, Juan José, Debanne, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428268/
https://ncbi.nlm.nih.gov/pubmed/28331203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00388-1
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