Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype

Most tumors undergo metabolic reprogramming towards glycolysis, the so-called Warburg effect, to support growth and survival. Overexpression of IF1, the physiological inhibitor of the F0F1ATPase, has been related to this phenomenon and appears to be a relevant marker in cancer. Environmental contrib...

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Udgivet i:Sci Rep
Main Authors: Hardonnière, Kévin, Fernier, Morgane, Gallais, Isabelle, Mograbi, Baharia, Podechard, Normand, Le Ferrec, Eric, Grova, Nathalie, Appenzeller, Brice, Burel, Agnès, Chevanne, Martine, Sergent, Odile, Huc, Laurence, Bortoli, Sylvie, Lagadic-Gossmann, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428028/
https://ncbi.nlm.nih.gov/pubmed/28298645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00269-7
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