Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding

Rationale: Cystic fibrosis (CF) lung disease progresses by a combination of airway inflammation, bacterial colonization, and infection. Airway inflammation is predominantly neutrophilic and complicates airway clearance therapies through cellular debris; excessive DNA; excessive and viscous mucus; an...

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Publicado en:Ann Am Thorac Soc
Autores principales: Zeitlin, Pamela L., Diener-West, Marie, Callahan, Karen A., Lee, Seakwoo, Talbot, C. Conover, Pollard, Bette, Boyle, Michael P., Lechtzin, Noah
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427734/
https://ncbi.nlm.nih.gov/pubmed/28006108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201608-649OC
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