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Nuclear-targeted siRNA delivery for long-term gene silencing
Developing effective nonviral siRNA delivery systems for long-term gene silencing remains a great challenge. Here we present a nuclear-targeted siRNA delivery system that can induce long-term gene silencing in cancer cells. The nanocarrier consists of gold nanoparticles modified with a dense shell o...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427680/ https://ncbi.nlm.nih.gov/pubmed/28553519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04293g |
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