Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration

AIMS: Clonidine is used for sedation in the paediatric intensive care unit. Extracorporeal membrane oxygenation (ECMO) provides temporary support if respiratory and cardiac function is threatened. ECMO influences the pharmacokinetics of drugs. Clonidine during paediatric ECMO cannot be effectively t...

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Bibliografische gegevens
Gepubliceerd in:Br J Clin Pharmacol
Hoofdauteurs: Kleiber, Niina, Mathôt, Ron A. A., Ahsman, Maurice J., Wildschut, Enno D., Tibboel, Dick, de Wildt, Saskia N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Pharmacokinetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427246/
https://ncbi.nlm.nih.gov/pubmed/28078682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13235
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