Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration

AIMS: Clonidine is used for sedation in the paediatric intensive care unit. Extracorporeal membrane oxygenation (ECMO) provides temporary support if respiratory and cardiac function is threatened. ECMO influences the pharmacokinetics of drugs. Clonidine during paediatric ECMO cannot be effectively t...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kleiber, Niina, Mathôt, Ron A. A., Ahsman, Maurice J., Wildschut, Enno D., Tibboel, Dick, de Wildt, Saskia N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427246/
https://ncbi.nlm.nih.gov/pubmed/28078682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13235
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