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Microanalysis of β-Lactam Antibiotics and Vancomycin in Plasma for Pharmacokinetic Studies in Neonates

Rational dosing of antibiotics in neonates should be based on pharmacokinetic (PK) parameters assessed in specific populations. PK studies of neonates are hampered by the limited total plasma volume, which restricts the sample volume and sampling frequency. Available drug assay methods require large...

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Detalhes bibliográficos
Main Authors: Ahsman, Maurice J., Wildschut, Enno D., Tibboel, Dick, Mathot, Ron A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612158/
https://ncbi.nlm.nih.gov/pubmed/18955527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00636-08
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