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Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib

PURPOSE: Tyrosine kinase inhibitors like sunitinib and sorafenib are commonly used to treat metastatic renal cell cancer patients. Cubilin is a membrane protein expressed in the proximal renal tubule. Cubilin and megalin function together as endocytic receptors mediating uptake of many proteins. The...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cancer Res Clin Oncol
Päätekijät: Niinivirta, Marjut, Enblad, Gunilla, Edqvist, Per-Henrik, Pontén, Fredrik, Dragomir, Anca, Ullenhag, Gustav J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427164/
https://ncbi.nlm.nih.gov/pubmed/28260162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-017-2365-y
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