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Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib
PURPOSE: Tyrosine kinase inhibitors like sunitinib and sorafenib are commonly used to treat metastatic renal cell cancer patients. Cubilin is a membrane protein expressed in the proximal renal tubule. Cubilin and megalin function together as endocytic receptors mediating uptake of many proteins. The...
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| Publicado no: | J Cancer Res Clin Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427164/ https://ncbi.nlm.nih.gov/pubmed/28260162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-017-2365-y |
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