Pregnancy reprograms large-conductance Ca(2+)-activated K(+) channel in uterine arteries: roles of TET-mediated active demethylation

The large conductance Ca(2+)-activated K(+) (BK(Ca)) channel is of critical importance in pregnancy-mediated increase in uterine artery vasodilation and blood flow. The present study tested the hypothesis that active DNA demethylation plays a key role in pregnancy-induced reprogramming and upregulat...

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Foilsithe in:Hypertension
Main Authors: Hu, Xiang-Qun, Dasgupta, Chiranjib, Chen, Man, Xiao, Daliao, Huang, Xiaohui, Han, Limin, Yang, Shumei, Xu, Zhice, Zhang, Lubo
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426984/
https://ncbi.nlm.nih.gov/pubmed/28396535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09059
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