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PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells

How nuclear size is regulated is a fundamental cell-biological question with relevance to cancers, which often exhibit enlarged nuclei. We previously reported that conventional protein kinase C (cPKC) contributes to nuclear size reductions that occur during early Xenopus development. Here we report...

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Publicado en:Mol Biol Cell
Main Authors: Edens, Lisa J., Dilsaver, Matthew R., Levy, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426852/
https://ncbi.nlm.nih.gov/pubmed/28356420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-11-0786
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