Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex

Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human bone marrow and fetal liver. This exclusive restriction of the virus replication to human erythroid progenitor cells...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Ganaie, Safder S., Zou, Wei, Xu, Peng, Deng, Xuefeng, Kleiboeker, Steve, Qiu, Jianming
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426800/
https://ncbi.nlm.nih.gov/pubmed/28459842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006370
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