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HNF1α defect influences post-prandial lipid regulation

PURPOSE: Hepatocyte nuclear factor 1 alpha (HNF1α) defects cause Mature Onset Diabetes of the Young type 3 (MODY3), characterized by defects in beta-cell insulin secretion. However, HNF1α is involved in many other metabolic pathways with relevance for monogenic or polygenic type 2 diabetes. We aimed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: St-Jean, Matthieu, Boudreau, François, Carpentier, André C., Hivert, Marie-France
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426708/
https://ncbi.nlm.nih.gov/pubmed/28493909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177110
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