Action of tyrosinase on alpha and beta-arbutin: A kinetic study

The known derivatives from hydroquinone, α and β-arbutin, are used as depigmenting agents. In this work, we demonstrate that the oxy form of tyrosinase (oxytyrosinase) hydroxylates α and β-arbutin in ortho position of the phenolic hydroxyl group, giving rise to a complex formed by met-tyrosinase wit...

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Bibliographic Details
Published in:PLoS One
Main Authors: Garcia-Jimenez, Antonio, Teruel-Puche, Jose Antonio, Berna, Jose, Rodriguez-Lopez, José Neptuno, Tudela, Jose, Garcia-Canovas, Francisco
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426667/
https://ncbi.nlm.nih.gov/pubmed/28493937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177330
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