Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women

BACKGROUND: In the HIV-1 vaccine trial RV144, ALVAC-HIV prime with an AIDSVAX(®) B/E boost reduced HIV-1 acquisition by 31% at 42 months post first vaccination. The bivalent AIDSVAX(®) B/E vaccine contains two gp120 envelope glycoproteins, one from the subtype B HIV-1 MN isolate and one from the sub...

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Udgivet i:PLoS One
Main Authors: Gilbert, Peter B., Excler, Jean-Louis, Tomaras, Georgia D., Carpp, Lindsay N., Haynes, Barton F., Liao, Hua-Xin, Montefiori, David C., Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Kaewkungwal, Jaranit, Kijak, Gustavo H., Tovanabutra, Sodsai, Francis, Donald P., Lee, Carter, Sinangil, Faruk, Berman, Phillip W., Premsri, Nakorn, Kunasol, Prayura, O’Connell, Robert J., Michael, Nelson L., Robb, Merlin L., Morrow, Rhoda, Corey, Lawrence, Kim, Jerome H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426618/
https://ncbi.nlm.nih.gov/pubmed/28493891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176428
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