Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

Cell-free circulating tumour DNA (ctDNA) in plasma has been shown to be informative of the genomic alterations present in tumours and has been used to monitor tumour progression and response to treatments. However, patients with brain tumours do not present with or present with low amounts of ctDNA...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: De Mattos-Arruda, Leticia, Mayor, Regina, Ng, Charlotte K. Y., Weigelt, Britta, Martínez-Ricarte, Francisco, Torrejon, Davis, Oliveira, Mafalda, Arias, Alexandra, Raventos, Carolina, Tang, Jiabin, Guerini-Rocco, Elena, Martínez-Sáez, Elena, Lois, Sergio, Marín, Oscar, de la Cruz, Xavier, Piscuoglio, Salvatore, Towers, Russel, Vivancos, Ana, Peg, Vicente, Cajal, Santiago Ramon y, Carles, Joan, Rodon, Jordi, González-Cao, María, Tabernero, Josep, Felip, Enriqueta, Sahuquillo, Joan, Berger, Michael F., Cortes, Javier, Reis-Filho, Jorge S., Seoane, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426516/
https://ncbi.nlm.nih.gov/pubmed/26554728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9839
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