Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis

BACKGROUND. Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is known about the pathophysiology. We hypothesized that the genotype of leukotriene A(4) hydrolase (encoded by LTA4H), which determines inflammatory eicosanoid expression, influences intracerebral...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Thuong, Nguyen T. T., Heemskerk, Dorothee, Tram, Trinh T. B., Thao, Le T. P., Ramakrishnan, Lalita, Ha, Vu T. N., Bang, Nguyen D., Chau, Tran T. H., Lan, Nguyen H., Caws, Maxine, Dunstan, Sarah J., Chau, Nguyen V. V., Wolbers, Marcel, Mai, Nguyen T. H., Thwaites, Guy E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426373/
https://ncbi.nlm.nih.gov/pubmed/28419368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix050
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