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Model-free extraction of spin label position distributions from pseudocontact shift data

A significant problem with paramagnetic tags attached to proteins and nucleic acids is their conformational mobility. Each tag is statistically distributed within a volume between 5 and 10 Angstroms across; structural biology conclusions from NMR and EPR work are necessarily diluted by this uncertai...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Suturina, Elizaveta A., Häussinger, Daniel, Zimmermann, Kaspar, Garbuio, Luca, Yulikov, Maxim, Jeschke, Gunnar, Kuprov, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426344/
https://ncbi.nlm.nih.gov/pubmed/28553510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03736d
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