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The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

BACKGROUND: For every six men, one will be diagnosed with prostate cancer (PCa) in their lifetime. Estrogen receptors (ERs) are known to play a role in prostate carcinogenesis. However, it is unclear whether the estrogenic effects are mediated by estrogen receptor α (ERα) or estrogen receptor β (ERβ...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Raza, Shaneabbas, Meyer, Megan, Goodyear, Casey, Hammer, Kimberly D. P., Guo, Bin, Ghribi, Othman
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425984/
https://ncbi.nlm.nih.gov/pubmed/28503095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-017-0422-x
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