COPD monocytes demonstrate impaired migratory ability

BACKGROUND: Increased lung macrophage numbers in COPD may arise from upregulation of blood monocyte recruitment into the lungs. CCR5 is a monocyte chemokine receptor regulated by interleukin-6 (IL-6); the concentration of CCR5 ligands are known to be elevated in COPD lungs. The objective of this stu...

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Udgivet i:Respir Res
Main Authors: Ravi, Arjun K, Plumb, Jonathan, Gaskell, Rosemary, Mason, Sarah, Broome, Caroline S, Booth, George, Catley, Matthew, Vestbo, Jørgen, Singh, Dave
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425971/
https://ncbi.nlm.nih.gov/pubmed/28494757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0569-y
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