Novel derivatives of phthalimide with potent anticonvulsant activity in PTZ and MES seizure models

OBJECTIVE(S): Phthalimide-based derivatives have anticonvulsant activity like as phenytoin by inhibition of sodium channel. In our previously research we mentioned about some phthalimide derivatives as potent anticonvulsant agents. MATERIALS AND METHODS: Fourteen analogs of 2-substituted phthalimide...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Davood, Asghar, Iman, Maryam, Pouriaiee, Hanieh, Shafaroodi, Hamed, Akhbari, Sepideh, Azimidoost, Leila, Imani, Erfan, Rahmatpour, Somaieh
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425926/
https://ncbi.nlm.nih.gov/pubmed/28804613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.8586
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