Novel derivatives of phthalimide with potent anticonvulsant activity in PTZ and MES seizure models

Objective(s): Phthalimide-based derivatives have anticonvulsant activity like as phenytoin by inhibition of sodium channel. In our previously research we mentioned about some phthalimide derivatives as potent anticonvulsant agents. Materials and Methods: Fourteen analogs of 2-substituted phthalimide...

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Bibliografiska uppgifter
Huvudupphovsmän: Asghar Davood, Maryam Iman, Hanieh Pouriaiee, Hamed Shafaroodi, Sepideh Akhbari, Leila Azimidoost, Erfan Imani, Somaieh Rahmatpour
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mashhad University of Medical Sciences 2017-04-01
Serie:Iranian Journal of Basic Medical Sciences
Ämnen:
Anticonvulsant
Docking
MES seizure
Phthalimide
PTZ seizure
Sodium channel
Länkar:http://ijbms.mums.ac.ir/article_8586_09ccb430c0f02e1c24ea319f9072bb44.pdf
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