Promyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming

Promyelocytic leukemia protein (PML), the main constituent of PML nuclear bodies, regulates various physiological processes in different cell types. However, little is known about its functions in embryonic stem cells (ESC). Here, we report that PML contributes to ESC self-renewal maintenance by con...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Hadjimichael, Christiana, Chanoumidou, Konstantina, Nikolaou, Christoforos, Klonizakis, Antonios, Theodosi, Gesthimani-Ioanna, Makatounakis, Takis, Papamatheakis, Joseph, Kretsovali, Androniki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425614/
https://ncbi.nlm.nih.gov/pubmed/28392218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.03.006
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