Promyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming

Promyelocytic leukemia protein (PML), the main constituent of PML nuclear bodies, regulates various physiological processes in different cell types. However, little is known about its functions in embryonic stem cells (ESC). Here, we report that PML contributes to ESC self-renewal maintenance by con...

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Udgivet i:Stem Cell Reports
Main Authors: Hadjimichael, Christiana, Chanoumidou, Konstantina, Nikolaou, Christoforos, Klonizakis, Antonios, Theodosi, Gesthimani-Ioanna, Makatounakis, Takis, Papamatheakis, Joseph, Kretsovali, Androniki
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425614/
https://ncbi.nlm.nih.gov/pubmed/28392218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.03.006
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