Promyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming

Promyelocytic leukemia protein (PML), the main constituent of PML nuclear bodies, regulates various physiological processes in different cell types. However, little is known about its functions in embryonic stem cells (ESC). Here, we report that PML contributes to ESC self-renewal maintenance by con...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Hadjimichael, Christiana, Chanoumidou, Konstantina, Nikolaou, Christoforos, Klonizakis, Antonios, Theodosi, Gesthimani-Ioanna, Makatounakis, Takis, Papamatheakis, Joseph, Kretsovali, Androniki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425614/
https://ncbi.nlm.nih.gov/pubmed/28392218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.03.006
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