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Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence

Cellular senescence is associated with aging and is considered a potential contributor to age-associated neurodegenerative disease. Exposure to ionizing radiation increases the risk of developing premature neurovascular degeneration and dementia but also induces premature senescence. As cells of the...

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Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: McRobb, Lucinda S., McKay, Matthew J., Gamble, Jennifer R., Grace, Michael, Moutrie, Vaughan, Santos, Estevam D., Lee, Vivienne S., Zhao, Zhenjun, Molloy, Mark P., Stoodley, Marcus A.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425125/
https://ncbi.nlm.nih.gov/pubmed/28437250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101225
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