Radiation-Stimulated Translocation of CD166 and CRYAB to the Endothelial Surface Provides Potential Vascular Targets on Irradiated Brain Arteriovenous Malformations

Vascular targeting with pro-thrombotic antibody-conjugates is a promising biological treatment for brain arteriovenous malformations (bAVMs). However, targeted drug delivery relies on the identification of unique or overexpressed markers on the surface of a target cell. In the absence of inherent bi...

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Detalhes bibliográficos
Main Authors: Lucinda S McRobb, Matthew J McKay, Andrew J Gauden, Vivienne S Lee, Sinduja Subramanian, Santhosh George Thomas, Markus KH Wiedmann, Vaughan Moutrie, Michael Grace, Zhenjun Zhao, Mark P Molloy, Marcus A Stoodley
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-11-01
Colecção:International Journal of Molecular Sciences
Assuntos:
brain arteriovenous malformation
endothelial cells
ionizing radiation
proteomics
stereotactic radiosurgery
vascular targeting
Acesso em linha:https://www.mdpi.com/1422-0067/20/23/5830
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