c-Fos and Dusp1 confer non-oncogene addiction in BCR-ABL induced leukemia

Tyrosine kinase inhibitor (TKI) therapy for human cancers is not curative, with relapse due to the continuing presence of tumor cells, referred to as minimal residual disease (MRD) cells. MRD stem or progenitor cells survival in the absence of oncogenic kinase signaling, a phenomenon referred to as...

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Vydáno v:Nat Med
Hlavní autoři: Kesarwani, Meenu, Kincaid, Zachary, Gomaa, Ahmed, Huber, Erika, Rohrabaugh, Sara, Siddiqui, Zain, Bouso, Muhammad F., Latif, Tahir, Xu, Ming, Komurov, Kakajan, Mulloy, James C., Cancelas, Jose A., Grimes, H. Leighton, Azam, Mohammad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424814/
https://ncbi.nlm.nih.gov/pubmed/28319094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4310
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