Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing

The CRISPR/Cas9 systems have revolutionized the field of genome editing by providing unprecedented control over gene sequences and gene expression in many species, including humans. Lentiviral vectors (LVs) are one of the primary delivery platforms for the CRISPR/Cas9 system due to their ability to...

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Bibliographic Details
Published in:Mol Ther Methods Clin Dev
Main Authors: Ortinski, Pavel I., O’Donovan, Bernadette, Dong, Xiaoyu, Kantor, Boris
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424571/
https://ncbi.nlm.nih.gov/pubmed/28497073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.04.002
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