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MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway

BACKGROUND: Cardiomyocyte apoptosis is a common pathological manifestation that occurs in several heart diseases. This study aimed to explore the mechanism of microRNA-486 (miR-486) in cardiomyocyte apoptosis by interfering with the p53-activated BCL-2 associated mitochondrial pathway. METHODS: miR-...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: Sun, Yuhan, Su, Qiang, Li, Lang, Wang, Xiantao, Lu, Yuanxi, Liang, Jiabao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424355/
https://ncbi.nlm.nih.gov/pubmed/28486954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-017-0549-7
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