The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis

O-GlcNAcylation has been implicated in the tumorigenesis of various tissue origins, but its function in liver tumorigenesis is not clear. Here, we demonstrate that O-GlcNAcylation can enhance the expression, stability and function of Yes-associated protein (YAP), the downstream transcriptional regul...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Xiao, Qiao, Yongxia, Wu, Qi, Chen, Yan, Zou, Shaowu, Liu, Xiangfan, Zhu, Guoqing, Zhao, Yinghui, Chen, Yuxin, Yu, Yongchun, Pan, Qiuhui, Wang, Jiayi, Sun, Fenyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424161/
https://ncbi.nlm.nih.gov/pubmed/28474680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15280
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