Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Single-cell transcriptome profiling of tumour tissue isolates allows the characterization of heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we adopt this powerful approach to breast cancer and analyse 515 cells from 11 patients. Inferred copy number variations from...

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Foilsithe in:Nat Commun
Main Authors: Chung, Woosung, Eum, Hye Hyeon, Lee, Hae-Ock, Lee, Kyung-Min, Lee, Han-Byoel, Kim, Kyu-Tae, Ryu, Han Suk, Kim, Sangmin, Lee, Jeong Eon, Park, Yeon Hee, Kan, Zhengyan, Han, Wonshik, Park, Woong-Yang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424158/
https://ncbi.nlm.nih.gov/pubmed/28474673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15081
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