PHLI-seq: constructing and visualizing cancer genomic maps in 3D by phenotype-based high-throughput laser-aided isolation and sequencing

Spatial mapping of genomic data to tissue context in a high-throughput and high-resolution manner has been challenging due to technical limitations. Here, we describe PHLI-seq, a novel approach that enables high-throughput isolation and genome-wide sequence analysis of single cells or small numbers...

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Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Kim, Sungsik, Lee, Amos Chungwon, Lee, Han-Byoel, Kim, Jinhyun, Jung, Yushin, Ryu, Han Suk, Lee, Yongju, Bae, Sangwook, Lee, Minju, Lee, Kyungmin, Kim, Ryong Nam, Park, Woong-Yang, Han, Wonshik, Kwon, Sunghoon
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176506/
https://ncbi.nlm.nih.gov/pubmed/30296938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1543-9
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