Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death

Hereditary pancreatitis (HP) is an autosomal dominant disease that displays the features of both acute and chronic pancreatitis. Mutations in human cationic trypsinogen (PRSS1) are associated with HP and have provided some insight into the pathogenesis of pancreatitis, but mechanisms responsible for...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Athwal, T, Huang, W, Mukherjee, R, Latawiec, D, Chvanov, M, Clarke, R, Smith, K, Campbell, F, Merriman, C, Criddle, D, Sutton, R, Neoptolemos, J, Vlatković, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424103/
https://ncbi.nlm.nih.gov/pubmed/24722290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.120
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