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Measures of RNA metabolism rates: Toward a definition at the level of single bonds
We give an overview of experimental and computational methods to estimate RNA metabolism rates genome-wide. We then advocate a local definition of RNA metabolism rate at the level of individual phosphodiester bonds. Rates of formation and disappearance of individual bonds are unambiguously defined,...
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| Udgivet i: | Transcription |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423486/ https://ncbi.nlm.nih.gov/pubmed/27841720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1257972 |
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