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A link between transcription fidelity and pausing in vivo

Pausing by RNA polymerase is a major mechanism that regulates transcription elongation but can cause conflicts with fellow RNA polymerases and other cellular machineries. Here, we summarize our recent finding that misincorporation could be a major source of transcription pausing in vivo, and discuss...

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Vydáno v:Transcription
Hlavní autoři: Gamba, Pamela, James, Katherine, Zenkin, Nikolay
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423485/
https://ncbi.nlm.nih.gov/pubmed/28072558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1274812
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