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Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants
SUMMARY: Reading frame altering genomic variants can impact gene expression levels and the structure of protein products, thus potentially inducing disease phenotypes. Current annotation approaches report the impact of such variants in the context of altered DNA sequence only; attributes of the resu...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423451/ https://ncbi.nlm.nih.gov/pubmed/28122779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw820 |
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