The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense Against Infection

Pneumocystis pneumonia (PCP) remains a major cause of morbidity and mortality within immunocompromised patients. In this study, we examined the potential role of Mincle (Macrophage inducible C-type lectin) for host defense against Pneumocystis. Binding assays implementing soluble Mincle Carbohydrate...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kottom, Theodore J., Hebrink, Deanne M., Jenson, Paige E., Nandakumar, Vijayalakshmi, Wüthrich, Marcel, Wang, Huafeng, Klein, Bruce, Yamasaki, Sho, Lepenies, Bernd, Limper, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423441/
https://ncbi.nlm.nih.gov/pubmed/28298521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600744
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