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Comparison of Dichotomized and Distributional Approaches in Rare Event Clinical Trial Design: a Fixed Bayesian Design

This research was motivated by our goal to design an efficient clinical trial to compare two doses of docosahexaenoic acid supplementation for reducing the rate of earliest preterm births and/or preterm births. Dichotomizing continuous gestational age data using a classic binomial distribution will...

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Detalhes bibliográficos
Publicado no:J Appl Stat
Main Authors: Lei, Yang, Carlson, Susan, Yelland, Lisa N., Makrides, Maria, Gibson, Robert, Gajewski, Byron J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423361/
https://ncbi.nlm.nih.gov/pubmed/28503016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2016.1214244
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