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Comparison of Dichotomized and Distributional Approaches in Rare Event Clinical Trial Design: a Fixed Bayesian Design

This research was motivated by our goal to design an efficient clinical trial to compare two doses of docosahexaenoic acid supplementation for reducing the rate of earliest preterm births and/or preterm births. Dichotomizing continuous gestational age data using a classic binomial distribution will...

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Bibliografische gegevens
Gepubliceerd in:J Appl Stat
Hoofdauteurs: Lei, Yang, Carlson, Susan, Yelland, Lisa N., Makrides, Maria, Gibson, Robert, Gajewski, Byron J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423361/
https://ncbi.nlm.nih.gov/pubmed/28503016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2016.1214244
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