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Preparation, Optimization and Toxicity Evaluation of (SPION-PLGA) ±PEG Nanoparticles Loaded with Gemcitabine as a Multifunctional Nanoparticle for Therapeutic and Diagnostic Applications

The aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates SPION and Gemcitabine in PLGA ± PEG to form multifunctional drug delivery system. For this aim, super paramagnetic iron oxide nanoparticles (SPIONs) were simultaneously synthesized and encapsulated with Gem...

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Vydáno v:Iran J Pharm Res
Hlavní autoři: Hamzian, Nima, Hashemi, Maryam, Ghorbani, Mahdi, Bahreyni Toosi, Mohammad Hossein, Ramezani, Mohammad
Médium: Artigo
Jazyk:Inglês
Vydáno: Shaheed Beheshti University of Medical Sciences 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423230/
https://ncbi.nlm.nih.gov/pubmed/28496458
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