LRG1 mRNA expression in breast cancer associates with PIK3CA genotype and with aromatase inhibitor therapy outcome

1. BACKGROUND: PIK3CA is the most frequent somatic mutated oncogene in estrogen receptor (ER) positive breast cancer. We previously observed an association between PIK3CA genotype and aromatase inhibitors (AI) treatment outcome. This study now evaluates whether expression of mRNAs and miRs are linke...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Ramirez-Ardila, Diana E., Ruigrok-Ritstier, Kirsten, Helmijr, Jean C., Look, Maxime P., van Laere, Steven, Dirix, Luc, Berns, Els M.J.J., Jansen, Maurice P.H.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423197/
https://ncbi.nlm.nih.gov/pubmed/27491861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.07.004
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