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Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy

Circulating miRNAs are promising biomarkers in oncology but have not yet been implemented in the clinic given the lack of concordance across studies. In order to increase the cross‐studies reliability, we attempted to reduce and to control the circulating miRNA expression variability between patient...

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發表在:Mol Oncol
Main Authors: Vigneron, Nicolas, Meryet-Figuière, Matthieu, Guttin, Audrey, Issartel, Jean-Paul, Lambert, Bernard, Briand, Mélanie, Louis, Marie-Hélène, Vernon, Mégane, Lebailly, Pierre, Lecluse, Yannick, Joly, Florence, Krieger, Sophie, Lheureux, Stéphanie, Clarisse, Bénédicte, Leconte, Alexandra, Gauduchon, Pascal, Poulain, Laurent, Denoyelle, Christophe
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423189/
https://ncbi.nlm.nih.gov/pubmed/27083764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.03.005
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