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DNA damage signalling barrier, oxidative stress and treatment‐relevant DNA repair factor alterations during progression of human prostate cancer

The DNA damage checkpoints provide an anti‐cancer barrier in diverse tumour types, however this concept has remained unexplored in prostate cancer (CaP). Furthermore, targeting DNA repair defects by PARP1 inhibitors (PARPi) as a cancer treatment strategy is emerging yet requires suitable predictive...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Oncol
Main Authors: Kurfurstova, Daniela, Bartkova, Jirina, Vrtel, Radek, Mickova, Alena, Burdova, Alena, Majera, Dusana, Mistrik, Martin, Kral, Milan, Santer, Frederic R., Bouchal, Jan, Bartek, Jiri
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423169/
https://ncbi.nlm.nih.gov/pubmed/26987799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.02.005
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