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Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma
Recent clinical trials have demonstrated that targeting chromatin remodeling factors is as a promising strategy for the treatment of glioblastoma (GBM). We and others have shown constitutive activation of DNA damage response (DDR) pathways in gliomas and suggested that targeting the DDR may improve...
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| Publicado no: | Mol Oncol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423160/ https://ncbi.nlm.nih.gov/pubmed/26794465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.12.014 |
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